SCHEMBL6992098

SCHEMBL6992098

Cc1ccc(C)c(N2CCC(=O)N2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 11/20 0.66
HSD17B10 Q99714 1/20 0.50
G6PD P11413 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.43
HTT P42858 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 2/20 0.43
RECQL P46063 1/20 0.43
GAA P10253 1/20 0.41
DDB1 Q16531 1/20 0.41
CRBN Q96SW2 1/20 0.41
TSHR P16473 2/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9299293 0.79 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL25122532 0.75 CRBN (0.67) ALOX5HSD17B10ALDH1A1MEN1HTT
SCHEMBL2382690 0.75 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL10875404 0.75 ALOX5 (0.67) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL7536266 0.73 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL9645318 0.70 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL17059036 0.69 HSD17B10 (0.63) HSD17B10ALOX15ALDH1A1MEN1KMT2A
SCHEMBL10408464 0.68 HSD17B10 (0.56) HSD17B10ALDH1A1MEN1HTTKMT2A
SCHEMBL17059034 0.67 GAA (0.64) HSD17B10ALDH1A1MEN1KMT2AMAPT
SCHEMBL17244485 0.67 HSD17B10 (0.64) HSD17B10ALDH1A1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0913732-B1 Processing of lithographic printing plate precursors AGFA GEVAERT (BE) 2003-07-02 EP disclosed
EP-0989464-B1 Processing method and apparatus for production of lithographic printing plates AGFA GEVAERT (BE) 2003-01-02 EP disclosed
EP-0913731-B1 Processing of lithographic printing plate precursors AGFA GEVAERT (BE) 2002-05-29 EP disclosed
US-6300034-B1 LITHOGRAPHIC PRINTING PLATES; ANODIZED ALUMINUM SUPPORT, SILVER HALIDE EMULSIONS; INFORMATION-WISE EXPOSURE; PROPULSION, CIRCULATION AGFA-GEVAERT (BE) 2001-10-09 US disclosed
US-6228557-B1 ALUMINUM SUPPORT; IMAGE RECEIVER LAYER; SILVER HALIDE EMULSION; HOLDING TANKS, DRIVE ROLLERS AGFA-GEVAERT (BE) 2001-05-08 US disclosed
US-6093522-A DECOATING OF A SILVER HALIDE DIFFUSION TRANSFER PRINTING PLATE BY TREATING THE PLATE WITH A WASH LIQUOR OF AN AQUEOUS SOLUTION OF AT LEAST ONE ORGANIC OR INORGANIC ACID SALT AND HAVING A PH VALUE IN A RANGE OF FROM 8.4-13 AGFA-GEVAERT, N.V. (BE) 2000-07-25 US disclosed
US-6063554-A DECOATING OF A SILVER HALIDE DIFFUSION TRANSFER PRINTING PLATE BY TREATING WITH AQUEOUS SOLUTION CONTAINING AT LEAST ONE NONIONIC SURFACTANT AGFA-GEVAERT, N.V. (BE) 2000-05-16 US disclosed
EP-0990950-A1 Processing method and apparatus for imaged elements AGFA-GEVAERT N.V. (BE) 2000-04-05 EP disclosed
EP-0989464-A2 Processing method and apparatus for production of lithographic printing plates AGFA-GEVAERT N.V. (BE) 2000-03-29 EP disclosed
EP-0913732-A1 Processing of lithographic printing plate precursors AGFA-GEVAERT N.V. (BE) 1999-05-06 EP disclosed
EP-0913731-A1 Processing of lithographic printing plate precursors AGFA-GEVAERT N.V. (BE) 1999-05-06 EP disclosed