Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988670 | 0.88 | TKT (0.31) | TKT | |
| SCHEMBL9126768 | 0.86 | TKT (0.35) | TKT | |
| SCHEMBL9019796 | 0.81 | CYP3A4 (0.41) | TKTMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9125548 | 0.80 | — | — | |
| SCHEMBL6992857 | 0.79 | MEN1 (0.38) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL9127167 | 0.78 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL9019764 | 0.73 | PDE3A (0.38) | TKTMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9019826 | 0.69 | ALDH1A1 (0.37) | TKTMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9019807 | 0.69 | PDE3A (0.32) | TKTMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9845278 | 0.68 | SYK (0.31) | MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589335-B1 | N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means | HOECHST AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-5457091-A | N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |