SCHEMBL6992291

SCHEMBL6992291

CC(N)(CC/C=C(\F)CNCC=N)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GGT1 P19440 1/20 0.35
ARG1 P05089 1/20 0.33
ARG2 P78540 1/20 0.33
ACLY P53396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130513 1.00 GGT1 (0.35) GGT1ARG1ARG2ACLY
SCHEMBL6653415 1.00 GGT1 (0.35) GGT1ARG1ARG2ACLY
SCHEMBL6130499 1.00 GGT1 (0.35) GGT1ARG1ARG2ACLY
SCHEMBL6130511 1.00 GGT1 (0.35) GGT1ARG1ARG2ACLY
SCHEMBL6130672 1.00 GGT1 (0.35) GGT1ARG1ARG2ACLY
SCHEMBL6130497 1.00 GGT1 (0.35) GGT1ARG1ARG2ACLY
SCHEMBL6985494 0.86 GGT1 (0.30) GGT1
SCHEMBL6988040 0.84 GGT1 (0.36) GGT1ARG1ARG2
SCHEMBL6992201 0.84 GGT1 (0.36) GGT1ARG1ARG2
SCHEMBL6987981 0.84 GGT1 (0.33) GGT1ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1317421-A1 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS Pharmacia Corporation (US) 2003-06-11 EP claimed
WO-2002022562-A1 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS PHARMACIA CORPORATION (US) 2002-03-21 WO claimed
EP-1317421-A1 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS Pharmacia Corporation (US) 2003-06-11 EP disclosed
WO-2002022562-A1 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS PHARMACIA CORPORATION (US) 2002-03-21 WO disclosed