Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833715 | 0.89 | NR1H4 (0.45) | NR1H4KDM4EALDH1A1 | |
| SCHEMBL3835251 | 0.86 | NR1H4 (0.44) | NR1H4KDM4EALDH1A1 | |
| SCHEMBL4598886 | 0.85 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL6256758 | 0.85 | NR1H4 (0.50) | NR1H4 | |
| SCHEMBL3836167 | 0.85 | NR1H4 (0.45) | NR1H4KDM4EALDH1A1 | |
| SCHEMBL14677996 | 0.84 | NR1H4 (0.48) | NR1H4 | |
| SCHEMBL3833863 | 0.83 | NR1H4 (0.43) | NR1H4KDM4EALDH1A1 | |
| SCHEMBL6673376 | 0.83 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL5721660 | 0.83 | NR1H4 (0.45) | NR1H4KDM4EALDH1A1 | |
| SCHEMBL6026583 | 0.83 | NR1H4 (0.47) | NR1H4HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |