Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 3/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527603 | 0.93 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4741522 | 0.90 | NR1H4 (0.44) | NR1H4ELANECTSD | |
| SCHEMBL4596921 | 0.89 | NR1H4 (0.50) | NR1H4ELANECTSD | |
| SCHEMBL4729688 | 0.89 | NR1H4 (0.43) | NR1H4ELANECTSD | |
| SCHEMBL5327298 | 0.89 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4847539 | 0.88 | NR1H4 (0.51) | NR1H4ELANECTSD | |
| SCHEMBL4851757 | 0.88 | NR1H4 (0.48) | NR1H4ELANECTSD | |
| SCHEMBL6449480 | 0.87 | NR1H4 (0.43) | NR1H4ELANECTSD | |
| SCHEMBL5709249 | 0.87 | NR1H4 (0.56) | NR1H4ELANECTSD | |
| SCHEMBL4783554 | 0.87 | NR1H4 (0.43) | NR1H4ELANECTSDGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430040-A1 | BENZOTHIAZEPINE DERIVATIVES | Astrazeneca AB (SE) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003020710-A1 | BENZOTHIAZEPINE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-03-13 | — | — | WO | disclosed |