⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16581387 | 0.75 | CA2 (0.33) | — | |
| SCHEMBL13659022 | 0.75 | — | — | |
| SCHEMBL22899116 | 0.73 | — | — | |
| SCHEMBL233981 | 0.70 | — | — | |
| SCHEMBL16588334 | 0.70 | — | — | |
| SCHEMBL1016447 | 0.70 | — | — | |
| SCHEMBL4391948 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL26848358 | 0.67 | CYP1A2 (0.32) | — | |
| SCHEMBL4171688 | 0.67 | — | — | |
| SCHEMBL11957458 | 0.67 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183355-B2 | Method for the synthesis of oligonucleotide derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-05-22 | — | — | US | disclosed |
| US-20110245478-A1 | Method for the Synthesis of Oligonucleotide Derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-10-06 | — | — | US | disclosed |
| US-7951926-B2 | Method for the synthesis of oligonucleotide derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-05-31 | — | — | US | disclosed |
| US-20090124571-A1 | METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-05-14 | — | — | US | disclosed |