Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.63 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.46 |
| ▸ | OXTR | P30559 | 2/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992772 | 0.93 | AVPR1A (0.63) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6988420 | 0.90 | AVPR2 (0.55) | AVPR1AAVPR1BAVPR2OXTRTRPV4 | |
| SCHEMBL6989784 | 0.89 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6987519 | 0.86 | AVPR1A (0.63) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6989965 | 0.86 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6992930 | 0.86 | AVPR1A (0.63) | AVPR1AAVPR1B | |
| SCHEMBL6989154 | 0.84 | AVPR1A (0.73) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6992887 | 0.84 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6992370 | 0.84 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6991594 | 0.83 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |