Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 8/20 | 0.67 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | OXTR | P30559 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992370 | 0.93 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2OXTRHDAC1 | |
| SCHEMBL6993624 | 0.92 | AVPR1A (0.66) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6992664 | 0.89 | AVPR1A (0.63) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6987519 | 0.89 | AVPR1A (0.63) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6991947 | 0.89 | AVPR1A (0.65) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6994643 | 0.86 | AVPR1A (0.66) | AVPR1AAVPR1BAVPR2RAB9AOXTR | |
| SCHEMBL6992362 | 0.86 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6989817 | 0.86 | AVPR1A (0.66) | AVPR1AAVPR1BNPC1MAPTRAB9A | |
| SCHEMBL6988967 | 0.85 | AVPR1A (0.69) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6987256 | 0.84 | AVPR1A (0.69) | AVPR1AAVPR1BAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |