Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29694602 | 0.81 | SLC6A2 (0.36) | ELANEALDH1A1NPSR1GPR55MAPT | |
| SCHEMBL23456695 | 0.81 | SLC6A2 (0.36) | ELANEALDH1A1NPSR1GPR55MAPT | |
| SCHEMBL22286445 | 0.80 | SLC6A2 (0.40) | ELANEALDH1A1NPSR1MAPTHSD17B10 | |
| SCHEMBL29728484 | 0.80 | SLC6A2 (0.40) | ELANEALDH1A1NPSR1MAPTHSD17B10 | |
| SCHEMBL7512573 | 0.79 | ELANE (0.44) | ELANEALDH1A1NPSR1GPR55MAPT | |
| SCHEMBL6987940 | 0.78 | ELANE (0.48) | ELANEALDH1A1NPSR1GPR55MAPT | |
| SCHEMBL19279084 | 0.78 | SLC6A2 (0.40) | ELANEALDH1A1NPSR1GPR55MAPT | |
| SCHEMBL22286506 | 0.77 | ELANE (0.39) | ELANEALDH1A1NPSR1GPR55PTPN1 | |
| SCHEMBL29694594 | 0.77 | ELANE (0.39) | ELANEALDH1A1NPSR1GPR55PTPN1 | |
| SCHEMBL6987548 | 0.77 | ELANE (0.47) | ELANEALDH1A1NPSR1GPR55HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |