Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.51 |
| ▸ | SELE | P16581 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995489 | 0.86 | EDNRA (0.54) | ALDH1A1MAPTHPGDNPC1KDM4E | |
| SCHEMBL6998083 | 0.85 | ICAM1 (0.43) | ALDH1A1MAPTHPGDNPC1KDM4E | |
| SCHEMBL14691163 | 0.85 | MAPT (0.58) | ALDH1A1MAPTHPGDNPC1KDM4E | |
| SCHEMBL6992593 | 0.84 | ICAM1 (0.45) | ALDH1A1MAPTHPGDNPC1KDM4E | |
| SCHEMBL6196210 | 0.84 | RXFP1 (0.53) | ALDH1A1MAPTHPGDNPC1KDM4E | |
| SCHEMBL17149273 | 0.80 | KMT2A (0.45) | ALDH1A1MAPTHPGDNPC1KDM4E | |
| SCHEMBL9377114 | 0.79 | EDNRA (0.58) | HPGDICAM1SELELMNAVCAM1 | |
| SCHEMBL31351340 | 0.78 | HPGD (0.53) | ALDH1A1MAPTHPGDNPC1KDM4E | |
| SCHEMBL26661113 | 0.78 | HPGD (0.53) | ALDH1A1MAPTHPGDNPC1KDM4E | |
| SCHEMBL4633538 | 0.77 | NMT1 (0.62) | ALDH1A1MAPTHPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943618-B1 | 1,2-dioxetane derivative | MATSUMOTO MASAKATSU (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6218135-B1 | EASY TO HANDLE, HEAT STABLE, AND HIGH IN EMISSION EFFICIENCY; FOR IMMUNOASSAYS | Matsumoto, Masakatsu (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0943618-A2 | 1,2-dioxetane derivative | FUJIREBIO INC. (JP) | 1999-09-22 | — | — | EP | disclosed |