Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.53 |
| ▸ | SELE | P16581 | 2/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362508 | 0.89 | EDNRA (0.52) | EDNRAICAM1SELEVCAM1MAPT | |
| SCHEMBL30724572 | 0.87 | ICAM1 (0.58) | EDNRAICAM1SELEVCAM1MAPT | |
| SCHEMBL6993045 | 0.86 | ALDH1A1 (0.51) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL17173230 | 0.84 | MCL1 (0.48) | EDNRAICAM1SELEKMT2AMAPT | |
| SCHEMBL8920574 | 0.84 | EDNRA (0.50) | EDNRAICAM1SELEVCAM1MEN1 | |
| SCHEMBL9374943 | 0.84 | EDNRA (0.71) | EDNRAICAM1SELEVCAM1MAPT | |
| SCHEMBL11800981 | 0.83 | EDNRA (0.46) | EDNRAICAM1SELEKMT2AMAPT | |
| SCHEMBL15697543 | 0.81 | EDNRA (0.44) | EDNRAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL5040288 | 0.81 | ICAM1 (0.78) | EDNRAICAM1SELEVCAM1KMT2A | |
| SCHEMBL5219829 | 0.81 | EDNRA (0.54) | EDNRAICAM1SELEVCAM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943618-B1 | 1,2-dioxetane derivative | MATSUMOTO MASAKATSU (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6218135-B1 | EASY TO HANDLE, HEAT STABLE, AND HIGH IN EMISSION EFFICIENCY; FOR IMMUNOASSAYS | Matsumoto, Masakatsu (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0943618-A2 | 1,2-dioxetane derivative | FUJIREBIO INC. (JP) | 1999-09-22 | — | — | EP | disclosed |