Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.80 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991250 | 0.91 | NPY5R (0.79) | NPY5RCSNK2A2CSNK2A1TNIKCHRNA3 | |
| SCHEMBL7000363 | 0.89 | NPY5R (1.00) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6996444 | 0.86 | NPY5R (0.86) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6996984 | 0.86 | NPY5R (0.79) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6992705 | 0.85 | NPY5R (0.67) | NPY5R | |
| SCHEMBL6993517 | 0.83 | NPY5R (0.73) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6997112 | 0.82 | NPY5R (0.78) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6994126 | 0.82 | NPY5R (0.72) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6990690 | 0.82 | NPY5R (0.78) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6990826 | 0.80 | NPY5R (0.78) | NPY5RCSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |