Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 0.78 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996444 | 0.89 | NPY5R (0.86) | NPY5RCSNK2A2CSNK2A1HPGDSMEN1 | |
| SCHEMBL7000363 | 0.88 | NPY5R (1.00) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6992423 | 0.88 | NPY5R (0.68) | NPY5RNPC1RAB9A | |
| SCHEMBL6996984 | 0.84 | NPY5R (0.79) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6991250 | 0.84 | NPY5R (0.79) | NPY5RCSNK2A2CSNK2A1NPC1RAB9A | |
| SCHEMBL6993059 | 0.82 | NPY5R (0.80) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6993517 | 0.80 | NPY5R (0.73) | NPY5RCSNK2A2CSNK2A1CHRNA3KCNH2 | |
| SCHEMBL6990826 | 0.80 | NPY5R (0.78) | NPY5RCSNK2A2CSNK2A1HPGDSMEN1 | |
| SCHEMBL6990465 | 0.80 | NPY5R (0.95) | NPY5RNPC1RAB9A | |
| SCHEMBL6999633 | 0.79 | NPY5R (0.82) | NPY5RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |