Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993497 | 1.00 | KDM4E (0.41) | KDM4EHPGDALDH1A1HSD17B10HDAC8 | |
| SCHEMBL6996712 | 0.84 | ALB (0.47) | KDM4EHPGDALDH1A1HSD17B10MCL1 | |
| SCHEMBL6996716 | 0.84 | ALB (0.47) | KDM4EHPGDALDH1A1HSD17B10MCL1 | |
| SCHEMBL6992637 | 0.81 | KDM4E (0.41) | KDM4EHPGDALDH1A1HSD17B10HDAC8 | |
| SCHEMBL6992638 | 0.81 | KDM4E (0.41) | KDM4EHPGDALDH1A1HSD17B10HDAC8 | |
| SCHEMBL8533967 | 0.75 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10MCL1 | |
| SCHEMBL6989986 | 0.75 | ALB (0.51) | KDM4EHPGDALDH1A1MCL1MEN1 | |
| SCHEMBL6989987 | 0.75 | ALB (0.51) | KDM4EHPGDALDH1A1MCL1MEN1 | |
| SCHEMBL6991270 | 0.73 | KMT2A (0.58) | KDM4EHPGDALDH1A1MCL1MEN1 | |
| SCHEMBL6991265 | 0.73 | KMT2A (0.58) | KDM4EHPGDALDH1A1MCL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768311-B1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-5728709-A | COAGULANTS AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0768311-A1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |