Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534277 | 0.84 | MCL1 (0.46) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL8532132 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL8531046 | 0.76 | MCL1 (0.51) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL6993501 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL6993497 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL8531608 | 0.73 | MCL1 (0.46) | KDM4EHPGDMCL1MEN1KMT2A | |
| SCHEMBL5508959 | 0.71 | MCL1 (0.62) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL2732524 | 0.71 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL10084375 | 0.69 | — | — | |
| SCHEMBL986506 | 0.68 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728709-A | COAGULANTS AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |