⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furan SCHEMBL27952080 | 0.86 | MAPK1 (0.35) | — | |
| SCHEMBL11390221 | 0.79 | — | — | |
| SCHEMBL9047754 | 0.79 | — | — | |
| SCHEMBL253593 | 0.74 | — | — | |
| SCHEMBL16344279 | 0.74 | — | — | |
| SCHEMBL11393563 | 0.74 | — | — | |
| SCHEMBL15189923 | 0.74 | — | — | |
| SCHEMBL28304425 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL6050998 | 0.72 | HCAR2 (0.34) | — | |
| SCHEMBL27884837 | 0.72 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112494469-A | Application of metformin in preparation of medicament for preventing and/or treating scar | 吴学雷 | 2021-03-16 | — | — | CN | claimed |
| EP-0000649-B1 | 5-SUBSTITUTED-1,2-DIHYDRO-3H-PYRROLO(1,2-A)PYRROLE-1-CARBONITRILES AND PROCESS FOR THEIR CONVERSION TO THE CORRESPONDING 1-CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1981-03-25 | — | — | EP | claimed |
| CN-115177593-A | Glutamine granules and preparation method thereof | 锦州奥鸿药业有限责任公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-114552009-A | Low-temperature electrolyte and lithium ion battery containing same | 合肥国轩高科动力能源有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114028372-A | Application of glutamine as active ingredient in preparation of psoriasis treatment medicine, psoriasis treatment medicine and preparation method thereof | 中南大学湘雅医院 | 2022-02-11 | — | — | CN | disclosed |
| CN-112494469-A | Application of metformin in preparation of medicament for preventing and/or treating scar | 吴学雷 | 2021-03-16 | — | — | CN | disclosed |
| CN-109567186-A | A kind of increasing flesh composition and its manufacturing method | 北京康比特体育科技股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-101983259-B | Apparatus for forming metal thin film and method for forming metal thin film using same | INKTEC CO LTD | 2013-05-01 | — | — | CN | disclosed |
| CN-101983259-A | Apparatus for forming metal thin film and method for forming metal thin film using same | INKTEC CO LTD | 2011-03-02 | — | — | CN | disclosed |
| EP-0728758-B1 | Dioxopyrrolo-pyrrole derivatives | HOFFMANN LA ROCHE (CH) | 2003-10-15 | — | — | EP | disclosed |