Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.59 |
| ▸ | AVPR2 | P30518 | 13/20 | 0.59 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.52 |
| ▸ | OXTR | P30559 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990881 | 0.95 | AVPR2 (0.59) | AVPR1AAVPR2AVPR1BOXTRLMNA | |
| SCHEMBL6988950 | 0.93 | AVPR2 (0.60) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6989322 | 0.92 | AVPR1A (0.60) | AVPR1AAVPR2AVPR1BOXTRLMNA | |
| SCHEMBL6991600 | 0.87 | AVPR1A (0.58) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6987470 | 0.86 | AVPR1A (0.59) | AVPR1AAVPR2AVPR1BOXTRLMNA | |
| SCHEMBL6986446 | 0.85 | AVPR2 (0.71) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6984084 | 0.85 | AVPR2 (0.81) | AVPR1AAVPR2OXTR | |
| SCHEMBL6984131 | 0.85 | AVPR1A (0.59) | AVPR1AAVPR2AVPR1BOXTRLMNA | |
| SCHEMBL6993534 | 0.83 | AVPR1A (0.71) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6995626 | 0.83 | AVPR1A (0.57) | AVPR1AAVPR2AVPR1BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |