Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.71 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.71 |
| ▸ | OXTR | P30559 | 2/20 | 0.50 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984084 | 0.94 | AVPR2 (0.81) | AVPR2AVPR1AOXTR | |
| SCHEMBL6993624 | 0.91 | AVPR1A (0.66) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6988950 | 0.86 | AVPR2 (0.60) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6990881 | 0.86 | AVPR2 (0.59) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6993693 | 0.85 | AVPR1A (0.59) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6991600 | 0.85 | AVPR1A (0.58) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6991947 | 0.85 | AVPR1A (0.65) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6989393 | 0.84 | AVPR1A (0.66) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6994023 | 0.83 | AVPR1A (0.68) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8797804 | 0.83 | AVPR1A (1.00) | AVPR2AVPR1AOXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |