Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 13/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995330 | 0.99 | F10 (0.42) | FPR2FPR1F10CYP3A4CYP2D6 | |
| SCHEMBL6999615 | 0.90 | F10 (0.52) | F10PRSS1F2KCNH2PRSS2 | |
| SCHEMBL6989579 | 0.90 | PRSS1 (0.44) | FPR2F10PRSS1F2IDO1 | |
| SCHEMBL6993192 | 0.89 | F10 (0.44) | FPR2F10PRSS1F2IDO1 | |
| SCHEMBL6996683 | 0.88 | F10 (0.53) | F10PRSS1F2KCNH2PRSS2 | |
| SCHEMBL6991785 | 0.87 | F10 (0.54) | F10PRSS1F2KCNH2PRSS2 | |
| SCHEMBL7143506 | 0.83 | USP30 (0.44) | FPR2FPR1F10CYP3A4CYP2D6 | |
| SCHEMBL7093219 | 0.83 | USP30 (0.45) | FPR2FPR1F10CYP3A4CYP2D6 | |
| SCHEMBL7401213 | 0.82 | F10 (0.40) | F10PRSS1F2KCNH2PRSS2 | |
| SCHEMBL6990138 | 0.80 | PRSS1 (0.54) | F10PRSS1F2KCNH2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303482-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008177-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |