⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207437 | 0.65 | — | — | |
| SCHEMBL511838 | 0.53 | — | — | |
| SCHEMBL6234127 | 0.53 | — | — | |
| SCHEMBL1903027 | 0.53 | — | — | |
| SCHEMBL12179431 | 0.47 | — | — | |
| SCHEMBL3078597 | 0.41 | — | — | |
| SCHEMBL2704746 | 0.37 | — | — | |
| SCHEMBL186926 | 0.37 | — | — | |
| SCHEMBL11204917 | 0.37 | — | — | |
| SCHEMBL13719381 | 0.33 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230942-B1 | THIENO-1,4-DIAZEPINES | BOEHRINGER INGELHEIM KG (DE) | 1992-04-29 | — | — | EP | claimed |
| US-4900729-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1990-02-13 | — | — | US | claimed |
| EP-0230942-A2 | Thieno-1,4-diazepines | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | claimed |
| EP-4629984-A1 | DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS | BioVentures, LLC (US) | 2025-10-15 | — | — | EP | disclosed |
| US-20250130239-A1 | PROTEIN DEGRADER | UNIVERSITY OF DUNDEE (GB) | 2025-04-24 | — | — | US | disclosed |
| EP-4405472-A1 | PROTEIN DEGRADER | University of Dundee (GB) | 2024-07-31 | — | — | EP | disclosed |
| WO-2024123929-A1 | DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS | BIOVENTURES, LLC (US) | 2024-06-13 | — | — | WO | disclosed |
| WO-2023047121-A1 | PROTEIN DEGRADER | UNIVERSITY OF DUNDEE (GB) | 2023-03-30 | — | — | WO | disclosed |
| US-20220119416-A9 | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-21 | — | — | US | disclosed |
| US-20210221826-A1 | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-22 | — | — | US | disclosed |
| US-10913752-B2 | Bivalent bromodomain inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| EP-0230942-B1 | THIENO-1,4-DIAZEPINES | BOEHRINGER INGELHEIM KG (DE) | 1992-04-29 | — | — | EP | disclosed |
| US-4900729-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1990-02-13 | — | — | US | disclosed |
| US-4900729-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1990-02-13 | — | — | US | disclosed |
| US-4900729-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0230942-A2 | Thieno-1,4-diazepines | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |
| EP-0230942-A2 | Thieno-1,4-diazepines | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |
| EP-0230942-A2 | Thieno-1,4-diazepines | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |
| US-4199588-A | TRANQUILIZERS, MUSCLE RELAXANTS, ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-04-22 | — | — | US | disclosed |
| US-4094984-A | ANTICONVULSANTS, TENSION RELIEVING AGENTS, MUSCLE RELAXANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1978-06-13 | — | — | US | disclosed |