Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 17/20 | 0.86 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994136 | 0.95 | NPY5R (0.89) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6994138 | 0.93 | NPY5R (1.00) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6998923 | 0.87 | NPY5R (0.80) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6992676 | 0.84 | NPY5R (1.00) | NPY5R | |
| SCHEMBL6994443 | 0.81 | NPY5R (0.79) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6996863 | 0.80 | NPY5R (1.00) | NPY5RFLT3 | |
| SCHEMBL6993088 | 0.72 | NPY5R (0.76) | NPY5RGSK3B | |
| SCHEMBL6991821 | 0.71 | NPY5R (0.76) | NPY5RGSK3B | |
| SCHEMBL6998634 | 0.70 | NPY5R (0.63) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6999825 | 0.70 | NPY5R (0.74) | NPY5RFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |