Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 14/20 | 0.63 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994443 | 0.82 | NPY5R (0.79) | NPY5RFLT3USP30GSK3BMAPK8 | |
| SCHEMBL6998167 | 0.81 | NPY5R (0.67) | NPY5RFLT3USP30 | |
| SCHEMBL6994138 | 0.77 | NPY5R (1.00) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6994136 | 0.72 | NPY5R (0.89) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6994084 | 0.70 | NPY5R (0.86) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6991821 | 0.66 | NPY5R (0.76) | NPY5RUSP30GSK3BFOXO1 | |
| SCHEMBL6999024 | 0.66 | NPY5R (0.73) | NPY5RFLT3USP30 | |
| SCHEMBL6998923 | 0.66 | NPY5R (0.80) | NPY5RFLT3GSK3BMAPK8MAPK9 | |
| SCHEMBL6998964 | 0.65 | NPY5R (0.78) | NPY5RFLT3USP30 | |
| SCHEMBL6993088 | 0.65 | NPY5R (0.76) | NPY5RUSP30GSK3BFOXO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |