Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 0.63 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996409 | 0.84 | NPY5R (0.68) | NPY5R | |
| SCHEMBL6999159 | 0.82 | NPY5R (0.65) | NPY5RFLT3NTRK3NTRK2AAK1 | |
| SCHEMBL6992731 | 0.81 | NPY5R (0.64) | NPY5RFLT3NTRK3NTRK2AAK1 | |
| SCHEMBL6999783 | 0.81 | NPY5R (0.64) | NPY5RFLT3NTRK3NTRK2AAK1 | |
| SCHEMBL6996063 | 0.81 | NPY5R (0.87) | NPY5RFLT3NTRK3NTRK2AAK1 | |
| SCHEMBL6996005 | 0.78 | NPY5R (1.00) | NPY5RFLT3NTRK3NTRK2AAK1 | |
| SCHEMBL6996863 | 0.76 | NPY5R (1.00) | NPY5RFLT3NTRK3NTRK2AAK1 | |
| SCHEMBL6992797 | 0.75 | NPY5R (0.86) | NPY5RFLT3NTRK3NTRK2AAK1 | |
| SCHEMBL6998167 | 0.75 | NPY5R (0.67) | NPY5RFLT3NTRK3NTRK2AAK1 | |
| SCHEMBL6988738 | 0.72 | NPY5R (0.76) | NPY5RFLT3NTRK3NTRK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |