Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 0.74 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988507 | 0.85 | NPY5R (0.77) | NPY5RSMN1; SMN2 | |
| SCHEMBL6996005 | 0.85 | NPY5R (1.00) | NPY5RMEN1LMNAPKMMAPK1 | |
| SCHEMBL6995372 | 0.84 | NPY5R (1.00) | NPY5RHSD17B10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7000363 | 0.83 | NPY5R (1.00) | NPY5RCHRNA3 | |
| SCHEMBL6992719 | 0.81 | NPY5R (0.73) | NPY5R | |
| SCHEMBL7001040 | 0.81 | NPY5R (0.80) | NPY5RMEN1LMNAPKMMAPK1 | |
| SCHEMBL6999633 | 0.81 | NPY5R (0.82) | NPY5RGSK3AGSK3B | |
| SCHEMBL6996063 | 0.79 | NPY5R (0.87) | NPY5RMEN1LMNAPKMMAPK1 | |
| SCHEMBL6992743 | 0.78 | NPY5R (1.00) | NPY5RMEN1KMT2A | |
| SCHEMBL6992797 | 0.78 | NPY5R (0.86) | NPY5RMEN1LMNAPKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |