Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 12/20 | 1.00 |
| ▸ | ABL1 | P00519 | 4/20 | 0.47 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988507 | 0.87 | NPY5R (0.77) | NPY5RABL1FOXO1MAPTHPGD | |
| SCHEMBL6998436 | 0.85 | NPY5R (0.79) | NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL6992719 | 0.85 | NPY5R (0.73) | NPY5RFOXO1 | |
| SCHEMBL1119035 | 0.84 | NPY5R (1.00) | NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL6994427 | 0.84 | NPY5R (0.74) | NPY5RMEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL6992742 | 0.82 | NPY5R (1.00) | NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL6990465 | 0.81 | NPY5R (0.95) | NPY5RMAPT | |
| SCHEMBL6991924 | 0.81 | NPY5R (0.88) | NPY5RMAPT | |
| SCHEMBL6993101 | 0.81 | NPY5R (0.84) | NPY5R | |
| SCHEMBL6990411 | 0.80 | NPY5R (0.70) | NPY5RABL1FOXO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |