Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987722 | 1.00 | ALB (0.48) | ALBAPPMCL1GRIN2DGRIN3B | |
| SCHEMBL6990795 | 1.00 | ALB (0.48) | ALBAPPMCL1GRIN2DGRIN3B | |
| SCHEMBL6990796 | 1.00 | ALB (0.48) | ALBAPPMCL1GRIN2DGRIN3B | |
| SCHEMBL6992891 | 0.81 | ALB (0.46) | ALBAPPMCL1GRIN2DGRIN3B | |
| SCHEMBL6995707 | 0.81 | ALB (0.46) | ALBAPPMCL1GRIN2DGRIN3B | |
| SCHEMBL6991264 | 0.81 | ALB (0.46) | ALBAPPMCL1GRIN2DGRIN3B | |
| SCHEMBL6989986 | 0.79 | ALB (0.51) | ALBAPPMCL1GRIN2DGRIN3B | |
| SCHEMBL6989987 | 0.79 | ALB (0.51) | ALBAPPMCL1GRIN2DGRIN3B | |
| SCHEMBL5487013 | 0.75 | NFE2L2 (0.45) | MAPTF9PLAUNFE2L2KDM4E | |
| SCHEMBL5487009 | 0.75 | NFE2L2 (0.45) | MAPTF9PLAUNFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768311-B1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0768311-A1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |