Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18069705 | 0.88 | AGTR2 (0.52) | AGTR2PPARGAGTR1ABCB11EGFR | |
| Azilsartan SCHEMBL284893 | 0.85 | AGTR2 (0.68) | AGTR2PPARGAGTR1ABCB11EGFR | |
| Azilsartan SCHEMBL30604716 | 0.85 | AGTR2 (0.68) | AGTR2PPARGAGTR1ABCB11EGFR | |
| SCHEMBL13522287 | 0.85 | AGTR2 (0.51) | AGTR2PPARGAGTR1ABCB11EGFR | |
| Azilsartan SCHEMBL7017834 | 0.84 | AGTR2 (0.67) | AGTR2PPARGAGTR1ABCB11EGFR | |
| Azilsartan SCHEMBL7017842 | 0.84 | AGTR2 (0.67) | AGTR2PPARGAGTR1ABCB11EGFR | |
| SCHEMBL28683396 | 0.83 | AGTR2 (0.61) | AGTR2PPARGAGTR1 | |
| SCHEMBL7017670 | 0.83 | AGTR2 (0.59) | AGTR2PPARGAGTR1ABCB11EGFR | |
| Azilsartan SCHEMBL7017839 | 0.83 | AGTR2 (0.57) | AGTR2PPARGAGTR1ABCB11EGFR | |
| SCHEMBL844779 | 0.83 | AGTR2 (0.53) | AGTR2PPARGAGTR1ABCB11EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1356815-A1 | ANALGESIC AND ANTIINFLAMMATORY DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |