Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | TP53 | P04637 | 6/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994738 | 1.00 | MAPT (0.69) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL11246434 | 0.92 | MAPT (0.66) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL11329160 | 0.92 | MAPT (0.66) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL3246328 | 0.89 | MAPT (0.62) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL11601466 | 0.89 | MAPT (0.62) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL3246325 | 0.89 | MAPT (0.62) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL4482364 | 0.87 | MAPT (0.61) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL9049322 | 0.87 | MAPT (0.61) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL9049329 | 0.87 | MAPT (0.61) | MAPTKMT2AMEN1TP53MAPK1 | |
| SCHEMBL10001770 | 0.86 | MAPT (0.59) | MAPTKMT2AMEN1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921119-B1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-07-02 | — | — | EP | disclosed |
| US-6114360-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-09-05 | — | — | US | disclosed |
| US-6063804-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0921119-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-09 | — | — | EP | disclosed |