Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | TP53 | P04637 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | RAF1 | P04049 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994738 | 0.87 | MAPT (0.69) | MAPTKMT2ATP53MEN1MAPK1 | |
| SCHEMBL6994743 | 0.87 | MAPT (0.69) | MAPTKMT2ATP53MEN1MAPK1 | |
| SCHEMBL7827549 | 0.83 | — | — | |
| SCHEMBL3246325 | 0.82 | MAPT (0.62) | MAPTKMT2ATP53MEN1MAPK1 | |
| SCHEMBL3246328 | 0.82 | MAPT (0.62) | MAPTKMT2ATP53MEN1MAPK1 | |
| SCHEMBL11601466 | 0.82 | MAPT (0.62) | MAPTKMT2ATP53MEN1MAPK1 | |
| SCHEMBL11329160 | 0.80 | MAPT (0.66) | MAPTKMT2ATP53MEN1MAPK1 | |
| SCHEMBL11246434 | 0.80 | MAPT (0.66) | MAPTKMT2ATP53MEN1MAPK1 | |
| SCHEMBL9049322 | 0.80 | MAPT (0.61) | MAPTKMT2ATP53MEN1MAPK1 | |
| SCHEMBL9049329 | 0.80 | MAPT (0.61) | MAPTKMT2ATP53MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498448-B2 | Methods for the production of 3-methylamino-1-(thiene-2-yl)-propane-1-ol | BASF AKTIENGESELLSCHAFT (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20070083055-A1 | Methods for the production of 3-methylamino-1-(thiene-2-yl)-propane-1-ol | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070083055-A1 | Methods for the production of 3-methylamino-1-(thiene-2-yl)-propane-1-ol | RNGTT, TALDO1, DERA | MAPT 4135/4885KMT2A 1053/4885TP53 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.