Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7037163 | 0.99 | GRIN2B (0.60) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL6990168 | 0.86 | GRIN1 (0.65) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL6986594 | 0.86 | CARM1 (0.69) | GRIN2BGRIN1CYP3A4NFKB1MTOR | |
| Hydrochloric Acid SCHEMBL7035790 | 0.84 | CARM1 (0.67) | GRIN2BGRIN1GMNNCYP3A4NFKB1 | |
| SCHEMBL5399769 | 0.81 | GRIN2B (0.58) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL5399772 | 0.81 | GRIN2B (0.58) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL6992678 | 0.78 | DRD4 (0.56) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL5402985 | 0.78 | PRMT3 (0.71) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL7251485 | 0.77 | GRIN2B (0.57) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL7251489 | 0.77 | GRIN2B (0.57) | GRIN2BGRIN1GMNNTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345935-A2 | PIPERIDINE DERIVATIVES AS SUBTYPE SELECTIVE N-METHYL-D-ASPARTATE ANTAGONISTS | Warner-Lambert Company LLC (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050070-A2 | PIPERIDINE DERIVATIVES AS SUBTYPE SELECTIVE N-METHYL-D-ASPARTATE ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-06-27 | — | — | WO | disclosed |