Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.66 |
| ▸ | FNTB | P49356 | 18/20 | 0.66 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | SLC6A15 | Q9H2J7 | 2/20 | 0.43 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995047 | 1.00 | FNTA (0.66) | FNTAFNTBHRH1SLC6A15PTAFR | |
| SCHEMBL6995401 | 0.79 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6995404 | 0.79 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6993275 | 0.79 | FNTA (0.65) | FNTAFNTB | |
| SCHEMBL6993273 | 0.79 | FNTA (0.65) | FNTAFNTB | |
| SCHEMBL6995057 | 0.79 | FNTA (0.59) | FNTAFNTBHRH1SLC6A15 | |
| SCHEMBL6993788 | 0.77 | FNTA (0.65) | FNTAFNTBHRH1SLC6A15PTAFR | |
| SCHEMBL6993792 | 0.77 | FNTA (0.65) | FNTAFNTBHRH1SLC6A15PTAFR | |
| SCHEMBL6995407 | 0.74 | FNTA (0.75) | FNTAFNTBHRH1SLC6A15 | |
| SCHEMBL6991647 | 0.74 | FNTA (1.00) | FNTAFNTBSLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021448-B1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORP (US) | 2003-05-02 | — | — | EP | claimed |
| US-6130229-A | Tricyclic compounds having activity as RAS-FPT inhibitors | SCHERING CORPORATION (US) | 2000-10-10 | — | — | US | claimed |
| EP-1021448-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 2000-07-26 | — | — | EP | claimed |
| WO-1998015556-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 1998-04-16 | — | — | WO | claimed |
| EP-1021448-B1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6130229-A | Tricyclic compounds having activity as RAS-FPT inhibitors | SCHERING CORPORATION (US) | 2000-10-10 | — | — | US | disclosed |
| EP-1021448-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015556-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 1998-04-16 | — | — | WO | disclosed |