Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.72 |
| ▸ | MAOB | P27338 | 6/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.72 |
| ▸ | SDHA | P31040 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CALML3 | P27482 | 1/20 | 0.72 |
| ▸ | F10 | P00742 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995564 | 1.00 | MAOA (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6991565 | 0.93 | MAOB (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6991569 | 0.93 | MAOB (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6990519 | 0.89 | MAOA (0.79) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6990521 | 0.89 | MAOA (0.79) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6994762 | 0.87 | MAOA (0.71) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6994758 | 0.87 | MAOA (0.71) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7821512 | 0.85 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7834065 | 0.85 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7821517 | 0.85 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792273-B1 | BICYCLIC OXAZINE AND THIAZINE OXAZOLIDINONE ANTIBACTERIALS | UPJOHN CO (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-0792273-A1 | BICYCLIC OXAZINE AND THIAZINE OXAZOLIDINONE ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015130-A1 | BICYCLIC OXAZINE AND THIAZINE OXAZOLIDINONE ANTIBACTERIALS | PHARMACIA + UPJOHN COMPANY (US) | 1996-05-23 | — | — | WO | disclosed |