⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19742932 | 0.67 | — | — | |
| SCHEMBL8694480 | 0.67 | — | — | |
| SCHEMBL7703514 | 0.65 | — | — | |
| SCHEMBL3241098 | 0.63 | — | — | |
| SCHEMBL1009203 | 0.62 | — | — | |
| SCHEMBL6696867 | 0.62 | — | — | |
| SCHEMBL2078830 | 0.62 | — | — | |
| SCHEMBL21247921 | 0.62 | — | — | |
| SCHEMBL18705923 | 0.62 | — | — | |
| SCHEMBL2470905 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357806-A | It is used in particular for the organic molecule of photoelectric device | 辛诺拉有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-110279684-A | For treating the purposes of 2 agonist of formyl peptide receptor of ocular inflammatory disease | 阿勒根公司 | 2019-09-27 | — | — | CN | claimed |
| CN-110121499-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2019-08-13 | — | — | CN | claimed |
| CN-110092788-A | Substituted [1,2,4] triazol [1,5-a] pyrimidin-7-yl compound as PDE2 inhibitor | 达特神经科学(开曼)有限公司 | 2019-08-06 | — | — | CN | claimed |
| CN-105007909-B | Use of formyl peptide receptor 2 agonists for the treatment of ocular inflammatory diseases | 阿勒根公司 | 2019-06-28 | — | — | CN | claimed |
| CN-109627248-A | The method of level-one amine guiding building 6- (the bromo- 2- fluorophenyl of 4-) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-04-16 | — | — | CN | claimed |
| CN-109336824-A | The preparation of mek inhibitor and preparation comprising mek inhibitor | 诺华股份有限公司 | 2019-02-15 | — | — | CN | claimed |
| CN-108884044-A | PIPERIDINE DERIVATIVE | 大塚制药株式会社 | 2018-11-23 | — | — | CN | claimed |
| CN-105176930-A | Reprogramming cells | SCRIPPS RESEARCH INST | 2015-12-23 | — | — | CN | claimed |
| CN-105106199-A | Methods of using MEK inhibitors | EXELIXIS INC | 2015-12-02 | — | — | CN | claimed |
| CN-103764144-A | Synergistic combination of a PI3K inhibitor and a MEK inhibitor | NOVARTIS AG | 2014-04-30 | — | — | CN | claimed |
| CN-102532107-B | 4-substituted aniline-7-substituted alcoxylhomopiperazine-quinazoline derivatives, and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2014-03-12 | — | — | CN | claimed |
| CN-101679410-B | 2-[(2-substituted)-ind0lizin-3-yl]-2-oxo-acetamide derivatives as antifungal agents | F2G LTD | 2013-11-27 | — | — | CN | claimed |
| CN-102421754-B | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING SHIQIAO BIOPHAM CO LTD | 2013-11-27 | — | — | CN | claimed |
| CN-103396409-A | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors | ARRAY BIOPHARMA INC | 2013-11-20 | — | — | CN | claimed |
| CN-101801955-B | Pyrimidyl cyclopentanes as akt protein kinase inhibitors | ARRAY BIOPHARMA INC | 2013-05-08 | — | — | CN | claimed |
| EP-2421612-A1 | HETEROCYCLIC COMPOUNDS AS MEK INHIBITORS | Novartis AG (CH) | 2012-02-29 | — | — | EP | claimed |
| EP-2344453-A2 | ACTIVATORS OF HUMAN PYRUVATE KINASE | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2011-07-20 | — | — | EP | claimed |
| WO-2010121646-A1 | HETEROCYCLIC COMPOUNDS AS MEK INHIBITORS | NOVARTIS AG (CH) | 2010-10-28 | — | — | WO | claimed |
| WO-2010042867-A2 | ACTIVATORS OF HUMAN PYRUVATE KINASE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-04-15 | — | — | WO | claimed |