Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 5/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27157370 | 0.93 | SMN1; SMN2 (0.39) | KMOUSP30MGLLSMN1; SMN2NPC1 | |
| SCHEMBL6604572 | 0.84 | SCN4A (0.40) | KMOMGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL31517595 | 0.81 | MGLL (0.31) | USP30MGLLFAAH | |
| SCHEMBL6607433 | 0.81 | SCN4A (0.40) | KMOMGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL31708787 | 0.80 | SCN4A (0.43) | MGLLSMN1; SMN2NPC1RAB9AKCNJ6 | |
| SCHEMBL6602289 | 0.76 | SCN4A (0.42) | MGLLSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23213554 | 0.75 | NPC1 (0.44) | MGLLSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL30071467 | 0.70 | NPC1 (0.43) | MGLLSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL2629334 | 0.69 | DDB1 (0.46) | MGLLSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL30730269 | 0.69 | KDM4E (0.35) | KMOMGLLSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345909-A1 | PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002048114-A1 | PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2002-06-20 | — | — | WO | disclosed |