SCHEMBL6995918

SCHEMBL6995918

[CH]=COCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
IDO1 P14902 1/20 0.48
AGXT P21549 1/20 0.46
HTR1A P08908 1/20 0.41
DRD2 P14416 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A3 Q01959 2/20 0.40
MAOB P27338 2/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
PTGS1 P23219 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTGS2 P35354 1/20 0.40
HIF1A Q16665 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL666545 0.79 TSHR (0.57) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL27509183 0.79 TSHR (0.57) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL6873209 0.77 TSHR (0.55) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL292605 0.76 TSHR (0.48) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL27517563 0.76 TSHR (0.48) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL5190106 0.76 TSHR (0.48) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL25293204 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL1933327 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL901056 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL5954673 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103313971-A N-arylpyrazole (thio) carboxamides BAYER IP GMBH 2013-09-18 CN claimed
EP-1301512-A2 BICYCLIC HYDANTOIN DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION Bioscience AG (DE) 2003-04-16 EP claimed
WO-2002008227-A2 BICYCLIC HYDANTOIN DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2002-01-31 WO claimed
WO-2023101004-A1 OLEFIN RESIN, METHOD FOR MANUFACTURING SAME, AND APPLICATION FOR SAME 三井化学株式会社 2023-06-08 WO disclosed
CN-103313971-B N-arylpyrazole (thio) carboxamides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-02 CN disclosed
CN-103313971-A N-arylpyrazole (thio) carboxamides BAYER IP GMBH 2013-09-18 CN disclosed
EP-1301512-A2 BICYCLIC HYDANTOIN DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION Bioscience AG (DE) 2003-04-16 EP disclosed
WO-2002008227-A2 BICYCLIC HYDANTOIN DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2002-01-31 WO disclosed