SCHEMBL5190106

SCHEMBL5190106

C=C[CH]OC[12c]1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
IDO1 P14902 1/20 0.44
AGXT P21549 1/20 0.43
ALDH1A1 P00352 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA9 Q16790 3/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A3 Q01959 2/20 0.38
ALOX15 P16050 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
PTGS1 P23219 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS2 P35354 1/20 0.38
HIF1A Q16665 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
CA7 P43166 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
MAOB P27338 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL292605 1.00 TSHR (0.48) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL145091 0.81 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL16116275 0.80 TSHR (0.36) TSHRIDO1AGXTALDH1A1ALOX15
Ethylene SCHEMBL28940632 0.79 TSHR (0.50) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL11409221 0.78 CA1 (0.41) IDO1ALDH1A1CA1CA2CA9
SCHEMBL17615200 0.78 TSHR (0.44) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL22297344 0.78 TSHR (0.44) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL444619 0.78 LOXL2 (0.38) ALDH1A1CYP1A2CYP2C19KMT2A
Butadiene SCHEMBL2164210 0.76 TSHR (0.75) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL6995918 0.76 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1780204-A1 Use of 5-amino pyrazoles for fighting plant pathogenic fungi, new 5-amino pyrazoles, method for their production and agents containing them BASF AKTIENGESELLSCHAFT (DE) 2007-05-02 EP disclosed
EP-1779726-A1 Use of 5-amino pyrazoles for fighting plant pathogenic fungi, new 5-amino pyrazoles, method for their production and agents containing them BASF AKTIENGESELLSCHAFT (DE) 2007-05-02 EP disclosed
EP-1780208-A1 Use of 5-amino pyrazoles for fighting plant pathogenic fungi, new 5-amino pyrazoles, method for their production and agents containing them BASF AKTIENGESELLSCHAFT (DE) 2007-05-02 EP disclosed
EP-1780206-A1 Use of 5-amino pyrazoles for fighting plant pathogenic fungi, new 5-amino pyrazoles, method for their production and agents containing them BASF AKTIENGESELLSCHAFT (DE) 2007-05-02 EP disclosed