Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 17/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.57 |
| ▸ | LYN | P07948 | 1/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999682 | 0.84 | PRKCQ (0.61) | PRKCQPRKCDLYNEGFRPRKCH | |
| SCHEMBL6387025 | 0.82 | EGFR (0.47) | LRRK2EGFRERBB2 | |
| SCHEMBL6383564 | 0.82 | EGFR (0.47) | LRRK2EGFRERBB2 | |
| SCHEMBL6386483 | 0.82 | SRC (0.52) | LRRK2EGFRERBB2 | |
| SCHEMBL6383797 | 0.81 | EGFR (0.53) | LRRK2EGFRERBB2 | |
| SCHEMBL6384817 | 0.81 | EGFR (0.54) | PRKCQLRRK2EGFRERBB2 | |
| SCHEMBL6384857 | 0.81 | EGFR (0.52) | LRRK2EGFRERBB2 | |
| SCHEMBL6385354 | 0.81 | EGFR (0.50) | LRRK2EGFRERBB2 | |
| SCHEMBL6386476 | 0.81 | EGFR (0.54) | PRKCQLRRK2EGFRERBB2 | |
| SCHEMBL6383939 | 0.81 | EGFR (0.57) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117659-B1 | SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS | WYETH CORP (US) | 2003-12-03 | — | — | EP | claimed |