Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 16/20 | 0.96 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998564 | 0.94 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL3059034 | 0.89 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6626200 | 0.89 | ADORA3 (0.79) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6995607 | 0.87 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7001225 | 0.87 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6999453 | 0.87 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6627522 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL3066530 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7001061 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6630588 | 0.86 | ADORA3 (0.76) | ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069126-B1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMA CO LTD (JP) | 2003-05-28 | — | — | EP | claimed |
| US-6288070-B1 | Triazolopurine derivatives, medicinal composition containing the derivatives, adenosine A3 receptor compatibilizing agent, and asthmatic remedy | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-09-11 | — | — | US | claimed |
| EP-1069126-A1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-01-17 | — | — | EP | claimed |
| EP-1069126-B1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMA CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6288070-B1 | Triazolopurine derivatives, medicinal composition containing the derivatives, adenosine A3 receptor compatibilizing agent, and asthmatic remedy | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-1069126-A1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-01-17 | — | — | EP | disclosed |