Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.69 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | IGF1R | P08069 | 9/20 | 0.47 |
| ▸ | PLK1 | P53350 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | YES1 | P07947 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6997962 | 0.99 | FYN (0.68) | FYNKDRIGF1RPLK1CCNA2 | |
| SCHEMBL7000795 | 0.88 | FYN (0.56) | FYNKDRPLK1CCNA2CDK2 | |
| SCHEMBL6996576 | 0.88 | IGF1R (0.55) | FYNKDRIGF1RPLK1CCNA2 | |
| Hydrochloric Acid SCHEMBL7090934 | 0.86 | FYN (0.62) | FYNKDRIGF1RPLK1SRC | |
| Hydrochloric Acid SCHEMBL7002776 | 0.86 | FYN (0.66) | FYNKDRPLK1CCNA2CDK2 | |
| SCHEMBL7238195 | 0.86 | FYN (0.56) | FYNKDRIGF1RPLK1CCNA2 | |
| Hydrochloric Acid SCHEMBL8040264 | 0.84 | FYN (0.53) | FYNKDRPLK1CCNA2CDK2 | |
| SCHEMBL20485806 | 0.82 | FYN (1.00) | FYNKDRIGF1RPLK1 | |
| SCHEMBL30521660 | 0.82 | FYN (1.00) | FYNKDRIGF1RPLK1 | |
| Hydrochloric Acid SCHEMBL6997490 | 0.81 | FYN (0.59) | FYNKDRPLK1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989985-B1 | FUSED POLYCYCLIC 2-AMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LTD (GB) | 2003-11-05 | — | — | EP | claimed |