Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 12/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822042 | 0.90 | CALML3 (0.47) | CALML3MAOAMAOBCYP3A4CYP2C19 | |
| SCHEMBL6999280 | 0.85 | CALML3 (0.49) | CALML3MAOAMAOBCYP3A4CYP2C19 | |
| SCHEMBL7002526 | 0.85 | CALML3 (0.63) | CALML3MAOAMAOBCYP3A4CYP2C19 | |
| SCHEMBL7836393 | 0.84 | CALML3 (0.48) | CALML3MAOAMAOBCYP3A4CYP2C19 | |
| SCHEMBL1222294 | 0.81 | MAOB (0.50) | CALML3MAOAMAOB | |
| SCHEMBL1222291 | 0.81 | MAOB (0.50) | CALML3MAOAMAOB | |
| SCHEMBL8822095 | 0.80 | MAOA (0.69) | CALML3MAOAMAOB | |
| SCHEMBL6996606 | 0.79 | MAOA (0.45) | CALML3MAOAMAOBCYP3A4CYP2C19 | |
| SCHEMBL1032546 | 0.78 | MAOB (0.48) | CALML3MAOAMAOB | |
| SCHEMBL18770241 | 0.78 | MAOB (0.48) | CALML3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286998-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | AstraZeneca AB (SE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001081350-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ASTRAZENECA AB (SE) | 2001-11-01 | — | — | WO | disclosed |
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| EP-1082323-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca UK Limited (GB) | 2001-03-14 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999064417-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |