Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.31 |
| ▸ | TYMS | P04818 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6991853 | 0.99 | HDAC1 (0.35) | HDAC1HDAC3NR3C2EGFRCSF1R | |
| Hydrochloric Acid SCHEMBL7001589 | 0.87 | GBA1 (0.36) | NR3C2EGFRCSF1RHIF1AEPAS1 | |
| Hydrochloric Acid SCHEMBL6995850 | 0.82 | NR3C2 (0.33) | NR3C2 | |
| SCHEMBL7001780 | 0.80 | NR3C2 (0.34) | NR3C2 | |
| Hydrochloric Acid SCHEMBL6988645 | 0.79 | NR3C2 (0.33) | NR3C2 | |
| Hydrochloric Acid SCHEMBL6992156 | 0.78 | NR3C2 (0.33) | NR3C2HIF1AEPAS1 | |
| SCHEMBL6989624 | 0.74 | PARP1 (0.52) | HDAC1NR3C2 | |
| SCHEMBL6999827 | 0.73 | NOS1 (0.46) | — | |
| SCHEMBL7000588 | 0.71 | PARP1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL6999676 | 0.68 | PARP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | claimed |