Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 17/20 | 0.68 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996985 | 0.90 | AVPR2 (0.69) | AVPR2AVPR1AOXTR | |
| SCHEMBL7000720 | 0.81 | AVPR2 (1.00) | AVPR2AVPR1A | |
| SCHEMBL7001232 | 0.80 | AVPR2 (0.45) | AVPR2AVPR1A | |
| SCHEMBL5786827 | 0.80 | AVPR2 (0.64) | AVPR2AVPR1A | |
| SCHEMBL7000948 | 0.79 | AVPR2 (0.81) | AVPR2AVPR1A | |
| SCHEMBL7002895 | 0.79 | AVPR2 (0.56) | AVPR2AVPR1AOXTR | |
| SCHEMBL7001234 | 0.76 | AVPR2 (0.55) | AVPR2L3MBTL3 | |
| SCHEMBL5786186 | 0.74 | AVPR2 (0.52) | AVPR2AVPR1A | |
| SCHEMBL5783664 | 0.74 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL5626598 | 0.74 | AVPR2 (0.48) | AVPR2AVPR1AL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021444-B1 | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |