Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001610 | 0.82 | AVPR2 (0.71) | AVPR2AVPR1A | |
| SCHEMBL7001093 | 0.80 | AVPR2 (0.57) | AVPR2AVPR1A | |
| SCHEMBL6996980 | 0.80 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL7002895 | 0.75 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL7001234 | 0.71 | AVPR2 (0.55) | AVPR2 | |
| SCHEMBL6624320 | 0.70 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL6996985 | 0.70 | AVPR2 (0.69) | AVPR2AVPR1A | |
| SCHEMBL5783073 | 0.69 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL5626377 | 0.67 | AVPR1A (0.46) | AVPR2HSD11B1AVPR1A | |
| SCHEMBL2960698 | 0.66 | HSD17B3 (0.45) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021444-B1 | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |