Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.58 |
| ▸ | EGFR | P00533 | 6/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.52 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | BCR | P11274 | 3/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381846 | 0.86 | SRC (0.57) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6382681 | 0.85 | SRC (0.62) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6382448 | 0.85 | SRC (0.71) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6379594 | 0.83 | SRC (0.83) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6382299 | 0.80 | SRC (0.67) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6380643 | 0.80 | SRC (0.67) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6382190 | 0.79 | EGFR (0.54) | SRCEGFRERBB2RAF1 | |
| SCHEMBL6381997 | 0.79 | SRC (0.48) | SRCEGFRERBB2 | |
| SCHEMBL6384206 | 0.79 | SRC (0.49) | SRCEGFRERBB2 | |
| SCHEMBL6381747 | 0.78 | EGFR (0.58) | SRCEGFRERBB2RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973746-B1 | SUBSTITUTED 3-CYANO QUINOLINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |