SCHEMBL6997420

SCHEMBL6997420

CC(C)(Cc1nc2c(N)nc3ccccc3c2s1)NC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 20/20 0.61
TLR7 Q9NYK1 15/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1527985 0.81 TLR8 (0.59) TLR8TLR7
SCHEMBL4964660 0.78 TLR8 (0.61) TLR8TLR7
SCHEMBL2807850 0.77 TLR8 (0.57) TLR8TLR7
SCHEMBL29373816 0.76 TLR8 (1.00) TLR8TLR7
SCHEMBL482958 0.76 TLR8 (1.00) TLR8TLR7
SCHEMBL1528137 0.76 TLR8 (1.00) TLR8TLR7
SCHEMBL1528044 0.76 TLR8 (0.74) TLR8TLR7
SCHEMBL5767961 0.75 TLR8 (0.73) TLR8TLR7
Hydrochloric Acid SCHEMBL5765916 0.75 TLR8 (0.97) TLR8TLR7
SCHEMBL2810620 0.75 TLR8 (0.64) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1100802-B1 OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLINE-4-AMINES AND ANALOGS THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2003-09-24 EP claimed