SCHEMBL482958

SCHEMBL482958

CCCc1nc2c(N)nc3ccccc3c2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 20/20 1.00
TLR7 Q9NYK1 15/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373816 1.00 TLR8 (1.00) TLR8TLR7
Hydrochloric Acid SCHEMBL5765916 0.99 TLR8 (0.97) TLR8TLR7
SCHEMBL1528149 0.92 TLR8 (1.00) TLR8TLR7
SCHEMBL1527936 0.91 TLR8 (1.00) TLR8TLR7
SCHEMBL1528137 0.88 TLR8 (1.00) TLR8TLR7
Hydrochloric Acid SCHEMBL5767005 0.87 TLR8 (0.97) TLR8TLR7
SCHEMBL1527831 0.86 TLR8 (0.75) TLR8TLR7
SCHEMBL5767961 0.84 TLR8 (0.73) TLR8TLR7
SCHEMBL24052764 0.84 TLR8 (0.72) TLR8TLR7
SCHEMBL5767746 0.84 TLR8 (0.70) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12599557-B2 Liposomal sustained-release compositions containing a therapeutic drug and use thereof TLC BIOPHARMACEUTICALS, INC. (US) 2026-04-14 US claimed
EP-4683654-A1 SIRP VARIANTS AND USES THEREOF Li, Wangzhi (US) 2026-01-28 EP claimed
US-20260014092-A1 EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR USE FOR VACCINES AND FOR IMMUNOMODULATION AGS THERAPEUTICS SAS (FR) 2026-01-15 US claimed
US-12514936-B2 Composition comprising catalase, preparation method and use thereof and method for killing tumor cells BEIJING PHARBERS GENESIS PHARM-TECH CO., LTD. (CN) 2026-01-06 US claimed
EP-4637712-A1 NANOPARTICULATE FORMULATION Newimmune II, LLC (US) 2025-10-29 EP claimed
US-20250186486-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION BAYLOR COLLEGE OF MEDICINE (US) 2025-06-12 US claimed
EP-4559479-A2 DRUG DELIVERY COMPOSITIONS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-05-28 EP claimed
US-20250049915-A2 NANOPARTICULATE FORMULATION NEWIMMUNE II, LLC (US) 2025-02-13 US claimed
EP-4493166-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION Baylor College of Medicine (US) 2025-01-22 EP claimed
CN-119278032-A Enhancement of persistent antitumor immunity by multifactorial immunomodulation 贝勒医学院 2025-01-07 CN claimed
WO-2002102377-A1 IMMUNE RESPONSE MODIFIERS FOR THE TREATMENT OF PERIODONTAL DISEASE 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-12-27 WO claimed
JP-2002524392-A 2002-08-06 JP claimed
US-20020072528-A1 Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof 3M INNOVATIVE PROPERTIES COMPANY 2002-06-13 US claimed
US-20020058674-A1 Systems and methods for treating a mucosal surface 3M INNOVATIVE PROPERTIES COMPANY 2002-05-16 US claimed
US-20020016332-A1 Imidazo-, oxazolo- and thiazolo- pyridineamines and naphthyridineamines which may be fused to cycloalkyl or benzene rings as immune reponse modifiers 3M INNOVATIVE PROPERTIES COMPANY 2002-02-07 US claimed
WO-2001097795-A2 SYSTEMS AND METHODS FOR TREATING A MUCOSAL SURFACE 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-27 WO claimed
WO-2001074343-A2 METHOD FOR THE TREATMENT OF DERMAL LESIONS CAUSED BY ENVENOMATION 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-10-11 WO claimed
EP-1100802-A1 OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF 3M Innovative Properties Company (US) 2001-05-23 EP claimed
US-6110929-A IMMUNOMODULATORS WHICH INDUCE CYTOKINE BIOSYNTHESIS, INCLUDING INTERFERON AND/OR TUMOR BIOSYNTHESIS, NECROSIS FACTOR AND INHIBIT T-HELPER-TYPE 2 IMMUNE RESPONSE; FOR TREATMENT OF VIRAL AND NEOPLASTIC DISEASES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-08-29 US claimed
WO-2000006577-A1 OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-02-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072528-A1 Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof IFNG, THPO, IL2 TLR8 290/4885TLR7 109/4885
US-20250049915-A2 NANOPARTICULATE FORMULATION MYD88, CD47, TLR9 TLR8 12/4885TLR7 8/4885
US-20020058674-A1 Systems and methods for treating a mucosal surface INMT, ICOS, HRH2 TLR8 31/4885TLR7 4/4885
US-20260014092-A1 EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR USE FOR VACCINES AND FOR IMMUNOMODULATION TLR9, TLR1, TLR2 TLR8 7/4885TLR7 9/4885
US-12599557-B2 Liposomal sustained-release compositions containing a therapeutic drug and use thereof SGMS2, TLR7, SMPD1 TLR8 100/4885TLR7 2/4885
US-20020016332-A1 Imidazo-, oxazolo- and thiazolo- pyridineamines and naphthyridineamines which may be fused to cycloalkyl or benzene rings as immune reponse modifiers STING1, HRH4, ICOS TLR8 89/4885TLR7 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.