Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995563 | 0.84 | F10 (0.44) | F10CHEK1MAPTGAATDP1 | |
| SCHEMBL7001484 | 0.83 | GAA (0.57) | F10CHEK1MAPTGAAMEN1 | |
| Hydrochloric Acid SCHEMBL7004333 | 0.83 | F10 (0.43) | F10CHEK1MAPTGAATDP1 | |
| SCHEMBL6994637 | 0.83 | CHEK1 (0.56) | F10CHEK1MAPTGAATDP1 | |
| SCHEMBL7001717 | 0.80 | CHEK1 (0.49) | F10CHEK1MAPTGAATDP1 | |
| SCHEMBL7001282 | 0.80 | CHEK1 (0.48) | F10CHEK1MAPTGAAF2 | |
| Hydrochloric Acid SCHEMBL7000612 | 0.79 | CHEK1 (0.47) | F10CHEK1MAPTGAATDP1 | |
| Hydrochloric Acid SCHEMBL6999319 | 0.79 | GAA (0.51) | F10CHEK1MAPTGAATDP1 | |
| SCHEMBL6999051 | 0.75 | CHEK1 (0.56) | CHEK1MAPTGAATDP1MEN1 | |
| SCHEMBL20867740 | 0.74 | IDO1 (0.57) | F10POLBIDO1PCSK9EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189889-B1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INT LTD (IE) | 2003-12-17 | — | — | EP | disclosed |
| US-6541486-B1 | Used for treating ischemia, such as results from stroke or myocardial infarction, trauma, neurodegeneration, and inflammation. | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-04-01 | — | — | US | disclosed |
| EP-1189889-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | Elan Pharma International Limited (IE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075117-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2000-12-14 | — | — | WO | disclosed |