Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001717 | 0.90 | CHEK1 (0.49) | CHEK1GAAMEN1POLBMAPT | |
| SCHEMBL7001484 | 0.90 | GAA (0.57) | CHEK1GAAMEN1POLBMAPT | |
| SCHEMBL6999051 | 0.90 | CHEK1 (0.56) | CHEK1GAAMEN1POLBMAPT | |
| Hydrochloric Acid SCHEMBL6999319 | 0.89 | GAA (0.51) | CHEK1GAAMEN1POLBMAPT | |
| Hydrochloric Acid SCHEMBL7002030 | 0.89 | CHEK1 (0.54) | CHEK1GAAMEN1POLBMAPT | |
| SCHEMBL3790024 | 0.88 | GAA (0.58) | CHEK1GAAMEN1POLBMAPT | |
| SCHEMBL5736933 | 0.87 | CHEK1 (0.55) | CHEK1GAAMEN1POLBMAPT | |
| SCHEMBL3938941 | 0.85 | CHEK1 (0.57) | CHEK1GAAMEN1POLBMAPT | |
| SCHEMBL8599171 | 0.85 | CHEK1 (0.61) | CHEK1GAAMEN1POLBMAPT | |
| SCHEMBL6993181 | 0.85 | CHEK1 (0.54) | CHEK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189889-B1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INT LTD (IE) | 2003-12-17 | — | — | EP | claimed |
| EP-1189889-B1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INT LTD (IE) | 2003-12-17 | — | — | EP | disclosed |
| US-6541486-B1 | Used for treating ischemia, such as results from stroke or myocardial infarction, trauma, neurodegeneration, and inflammation. | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-04-01 | — | — | US | disclosed |
| EP-1189889-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | Elan Pharma International Limited (IE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075117-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2000-12-14 | — | — | WO | disclosed |