Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001183 | 0.87 | KCNH2 (0.46) | PTGS2PTGS1KCNH2CA1CA2 | |
| SCHEMBL6996714 | 0.85 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL7001297 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6996876 | 0.82 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6997658 | 0.80 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL6994499 | 0.79 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL6998616 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL6995648 | 0.79 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL6995203 | 0.79 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6993196 | 0.79 | PTGS2 (0.48) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | claimed |
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | disclosed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |