⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993840 | 0.90 | MEN1 (0.31) | — | |
| SCHEMBL12613657 | 0.85 | — | — | |
| SCHEMBL6998834 | 0.82 | — | — | |
| SCHEMBL19622520 | 0.71 | — | — | |
| SCHEMBL21236784 | 0.71 | — | — | |
| SCHEMBL18227311 | 0.65 | TSHR (0.36) | — | |
| SCHEMBL20130263 | 0.65 | MEN1 (0.33) | — | |
| SCHEMBL6141036 | 0.65 | — | — | |
| SCHEMBL8848780 | 0.65 | TSHR (0.34) | — | |
| SCHEMBL3183822 | 0.64 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183355-B2 | Method for the synthesis of oligonucleotide derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-05-22 | — | — | US | disclosed |
| US-20110245478-A1 | Method for the Synthesis of Oligonucleotide Derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-10-06 | — | — | US | disclosed |